Nest-o-patch 1.2

An intuitive application that enables you to analyze single channel properties and estimate parameters in patch-clamp recordings

Nest-o-patch is designed mainly for “preconditioning” and analysis of single channel properties in patch-clamp recordings. Single channel conductance, kinetics, NPo and open probability may be estimated. The program focused mainly on the analysis of level dwellings distribution in a recording with several channels and estimate of the number of channels (N) and open probability (Po). Analysis of hidden Markov models is planned in the future versions.

However, the program may be useful in various applications, for example, analysis of whole-cell mode recordings, or of any other data, when limited editing and measurements in a 2-dimentional (for example time-current) wave are required. The program itself does not make any assumptions about units of the recordings, it deals only with X-values and Y-values.